Timothy M Cox Selected Research

Neurodegenerative Diseases (Neurodegenerative Disease)

1/2023	Upregulation of non-canonical and canonical inflammasome genes associates with pathological features in Krabbe disease and related disorders.
5/2022	A novel brain-penetrant oral UGT8 inhibitor decreases in vivo galactosphingolipid biosynthesis in murine Krabbe disease.
11/2021	L-Arginine Ameliorates Defective Autophagy in GM2 Gangliosidoses by mTOR Modulation.
2/2012	GM2 gangliosidosis in a UK study of children with progressive neurodegeneration: 73 cases reviewed.
9/2011	Insights into Krabbe disease from structures of galactocerebrosidase.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Timothy M Cox Research Topics

Disease

38	Gaucher Disease (Gaucher's Disease) 05/2023 - 05/2003
8	Sandhoff Disease (Sandhoff's Disease) 11/2021 - 07/2006
7	Iron Overload 01/2015 - 03/2004
6	GM2 Gangliosidoses (GM2 Gangliosidosis) 11/2021 - 06/2009
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2023 - 09/2011
5	Globoid Cell Leukodystrophy (Krabbe Disease) 01/2023 - 09/2011
5	Neurologic Manifestations (Neurological Manifestations) 01/2023 - 02/2014
4	Osteonecrosis (Kienbock's Disease) 10/2021 - 01/2011
3	Pain (Aches) 01/2023 - 01/2015
3	Neoplasms (Cancer) 07/2015 - 05/2003
3	Hemochromatosis (Bronze Diabetes) 03/2010 - 05/2003
2	Disease Progression 01/2023 - 12/2010
2	Demyelinating Diseases (Demyelinating Disease) 01/2023 - 09/2011
2	Neuroinflammatory Diseases 11/2021 - 03/2015
2	Inborn Genetic Diseases (Disease, Hereditary) 10/2021 - 03/2004
2	Rare Diseases (Rare Disease) 01/2019 - 01/2012
2	Nervous System Diseases (Neurological Disorders) 01/2017 - 06/2009
2	Type C Niemann-Pick Disease (Niemann Pick Disease, Type C) 03/2016 - 08/2004
2	Parkinson Disease (Parkinson's Disease) 07/2015 - 02/2013
2	Lysosomal Storage Diseases (Lysosomal Storage Disease) 02/2014 - 10/2010
2	Tay-Sachs Disease 02/2012 - 07/2006
2	Hyperferritinemia 06/2011 - 08/2005
2	type 2 Hemochromatosis 10/2005 - 03/2004
1	Tuberculosis (Tuberculoses) 01/2023
1	Lung Diseases (Lung Disease) 01/2023
1	Mucopolysaccharidoses 12/2022
1	Bone Diseases (Bone Disease) 01/2022
1	Seizures (Absence Seizure) 01/2022
1	Cerebellar Diseases (Cerebellar Syndrome) 01/2022
1	Sphingolipidoses (Sphingolipidosis) 11/2021
1	Mucopolysaccharidosis VI (Syndrome, Maroteaux-Lamy) 12/2018
1	Cardiac Arrhythmias (Arrythmia) 01/2018
1	Thyrotoxicosis 01/2018
1	Thyroid Diseases (Thyroid Disease) 01/2018
1	Anemia 12/2016
1	Thrombocytopenia (Thrombopenia) 12/2016
1	Myocardial Infarction 06/2015
1	Psychotic Disorders (Schizoaffective Disorder) 06/2015
1	Body Weight (Weight, Body) 03/2015
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2015
1	Lymphoma (Lymphomas) 01/2015

Drug/Important Bio-Agent (IBA)

15	EnzymesIBA 01/2023 - 09/2005
13	Glucosylceramidase (Glucocerebrosidase)IBA 01/2023 - 05/2003
11	Glucosylceramides (Glucocerebrosides)IBA 01/2023 - 01/2004
10	eliglustatIBA 01/2023 - 10/2010
9	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2004
9	imiglucerase FDA Link 01/2023 - 01/2010
9	IronIBA 01/2015 - 11/2002
8	AcidsIBA 02/2019 - 12/2010
5	GalactosylceramidaseIBA 01/2023 - 09/2011
5	GlucosidasesIBA 01/2021 - 01/2015
5	Hexosaminidases (Hexosaminidase)IBA 12/2020 - 07/2006
5	miglustat (Zavesca)FDA Link 01/2017 - 05/2003
5	HepcidinsIBA 06/2011 - 03/2004
4	sphingosyl beta-glucosideIBA 01/2023 - 01/2015
4	GlycosphingolipidsIBA 12/2022 - 05/2003
4	ceramide glucosyltransferaseIBA 01/2017 - 10/2010
4	LipidsIBA 01/2017 - 08/2004
4	metal transporting protein 1 (ferroportin)IBA 09/2014 - 08/2005
3	Proteins (Proteins, Gene)FDA Link 12/2022 - 07/2006
3	ChemokinesIBA 07/2015 - 09/2005
3	CytokinesIBA 07/2015 - 09/2006
2	Psychosine (Galactosylsphingosine)IBA 05/2022 - 01/2017
2	Galactosylceramides (Galactocerebrosides)IBA 05/2022 - 01/2017
2	Lysergic Acid Diethylamide (LSD)IBA 01/2022 - 02/2014
2	SphingolipidsIBA 11/2021 - 01/2010
2	Hexosaminidase A (Hex A)IBA 12/2020 - 01/2017
2	Chemokine CCL5IBA 01/2012 - 01/2011
2	Mannose (D-Mannose)IBA 01/2011 - 10/2004
2	chitotriosidaseIBA 01/2011 - 01/2004
2	G(M2) Ganglioside (Ganglioside GM2)IBA 04/2008 - 07/2006
2	Tartrate-Resistant Acid PhosphataseIBA 09/2006 - 10/2003
2	Transferrin Receptors (Transferrin Receptor)IBA 10/2005 - 05/2003
1	Lysophosphatidylcholines (Lysophosphatidylcholine)IBA 01/2023
1	venglustatIBA 01/2023
1	InflammasomesIBA 01/2023
1	Arginine (L-Arginine)FDA Link 11/2021
1	Protein Kinases (Protein Kinase)IBA 11/2021
1	Phosphotransferases (Kinase)IBA 11/2021
1	CDw17 antigen (lactosylceramide)IBA 01/2019
1	Proteasome InhibitorsIBA 01/2019
1	Bortezomib (Velcade)FDA Link 01/2019
1	N-Acetylgalactosamine-4-Sulfatase (Arylsulfatase B)IBA 12/2018
1	GlycosaminoglycansIBA 12/2018
1	Amiodarone (Amiodarona)FDA LinkGeneric 01/2018
1	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2017
1	Hemoglobins (Hemoglobin)IBA 01/2017
1	CholesterolIBA 03/2016
1	SphingosineIBA 07/2015
1	HydrolasesIBA 07/2015
1	ParaproteinsIBA 01/2015
1	heme arginateIBA 01/2015
1	N-(4-aminophenethyl)spiroperidol (NAPS)IBA 01/2015

Therapy/Procedure

21	Therapeutics 05/2023 - 05/2003
10	Enzyme Replacement Therapy 05/2023 - 10/2004
7	Enzyme Therapy 01/2017 - 05/2003
3	Splenectomy 10/2021 - 01/2011
2	Stem Cell Transplantation 01/2022 - 12/2010
2	Complementary Therapies (Alternative Medicine) 01/2017 - 02/2014
1	Transplantation 01/2022